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Botulinum toxin Wikipedia

Botulinum toxin Wikipedia

Botulinum toxin is the most acutely lethal toxin known. Intoxication can occur naturally as a result of either wound or intestinal infection or by ingesting preformed toxin in food. The estimated human median lethal dose (LD 50 ) of type A toxin is – ng /kg intravenously or intramuscularly, 10–13 ng/kg when inhaled, or 1000 ng/kg ...

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COMMITTEE FOR VETERINARY MEDICINAL PRODUCTS

COMMITTEE FOR VETERINARY MEDICINAL PRODUCTS

intake of 100 mg of atropine is considered the minimum lethal dose, in children a few milligrams. In case of (S)hyoscyamine an oral dose of 10 mg and more is said to be lethal in human adults. 6. Information on repeated dose toxicity was not available. 7. No studies on genotoxicity or reproductive effects including teratogenicity ofAtropa

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